Identification of metaflothionein in Pleurodeles waltl.
نویسندگان
چکیده
The characterization of metallothionein in the Urodele amphibian species Pleurodeles waltl was achieved. A simple and rapid method for identification of metallothionein, based on its strong affinity for cadmium (109Cd), was used. We were able to show that metallothionein is constitutively synthesized in liver, ovary and brain. The property of metallothionein to strongly bind essential (Zn, Cu) as well as toxic (Cd, Hg) metals is consistent with a dual role in cellular metabolism, ie. homeostatis and detoxification of heavy metal ions.
منابع مشابه
Cytogenetic Maps of Lampbrush Chromosomes of Newts of the Genus <Emphasis Type="Italic">Pleurodeles</Emphasis>: An Algorithm of Lampbrush Chromosome Identification in<Emphasis Type="Italic">Pleurodeles waltl</Emphasis> by Immunocytochemical Staining of Landmark Loops with Polyclonal Anti-Ro52 Antisera
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ورودعنوان ژورنال:
- Zeitschrift fur Naturforschung. C, Journal of biosciences
دوره 57 7-8 شماره
صفحات -
تاریخ انتشار 2002